• Sleep Apnea

    How can you tell if you have Sleep Apnea? Ask your spouse, family, or those around you. Here are some questions to ask: 1. Are you a loud, habitual snorer, disturbing your companion? 2. Do you feel tired and groggy in the morning? 3. Do you experience sleepiness and fatigue during the day? 4. Are you overweight? 5. Have you been observed to choke, gasp, or hold your breath during sleep? If you answered yes to one or more of these questions, you should discuss your symptoms with your physician. Blood oxygen saturation is reduced in the entire body during apnea -- sometimes producing serious irregular heartbeats and significantly reduced oxygen to the brain. Common symptoms of Sleep Apnea are a decreased ability to concentrate; loss of energy and/or fatigue; mild to marked depression; irritability; short temper; morning headaches; forgetfulness; anxiety; and, most frequently, excessive daytime sleepiness. Read More
  • Narcolepsy

    Narcolepsy, and related disorders, is typified by the inability to stay awake. Narcoleptics may suddenly fall asleep while they are engaged in an activity (for example, while waiting for a traffic light to change). Attacks are occasionally brought on by laughing, crying, and other strong emotions in a group setting. This illness often goes undiagnosed for years. Read More
  • Insomnia

    Insomnia is an inability to fall asleep or stay asleep. Attacks are often brought on by stress; worry; depression; another illness; persistent pain; and sleeping pill habits. Evaluating insomnia is important even if the condition seems temporary. Read More
  • Other Sleep Disorders

    Some people suffer from nightmares, night terrors, sleep walking, excessive body jerks, or uncontrollable leg movements. These people often get less than four and one-half hours of restorative sleep -something our bodies need. Even though a person spends ten hours in bed, they may only get two hours of restorative sleep. It is important to have your sleep analyzed if you find yourself waking up more tired than when you went to bed. Read More
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Prolonged Hypoxia in Man Without Circulatory Compromise Fails to Demonstrate Cerebral Pathology

M. A. RIE, and P. G. BERN AD, Boston, MA

This study attempted to determine whether hypoxia produces neuropathologic changes in human brain. Three previously healthy young adults (16-19 years) without known cerebral or cardiac disease developed acute respiratory hypoxia (PaOs < 45 mm Hg) of 1-8 days duration. Patients were monitored throughout their illness with continuous recording of mean intrn-arterial blood pressure (MAP) and frequent intermittent determination of cardiac output (CO), arterial (PaOz) and mixed venous (PvCfc) oxygen tensions. Each patient was found to be responsive and following commands until the day of death.

Duration of

hypoxemia (hrs)


PaO« (mm Hg)


CO (L/min)


MAP (mm Hg)

 192 30  8.00  55
 28 24 2.96 57
 31 38 * 80

*CO = 10.44 L/min 4 hrs prior to death.

In all cases measures were taken to maintain systemic blood pressure and flow at supernormal levels. The mode of death in each case was sudden refractory bradycardia unresponsive to maximal respiratory, vagolytic and cardiotonic therapies. Detailed pathologic examination of each brain by two neuropathologists unfamiliar with the clinical histories failed to reveal any of the pathologic changes that are known to be associated with ischemic-anoxic brain injury.

- April 1980 Neurology 30 Page 443
- Clinical Problems Page 182